This was partially inspired by a couple of PhD students from Cambridge, I met when they were on honeymoon in Tenerife. He was studying chemokines, when I was thinking about cytokines and cancer.
An old idea was that HIV made IL-4 on its own – with no IL-2 or IL-1+. I was wrong! After I met the Cambridge students I learned that HIV made three chemokines, that normally are produced in response to IL-4.
The difference is the feedback – my area of expertise. IL-4 causes the APCs to produce the active antibody, and enough IL-2 to action it.
Chemokines make the antibody with no IL-2, only the usually suppressive IL-10. This is what causes AIDs!
So if somebody is HIV+, we give them a drip of IL-2, at the level of a person getting better from an infection, even with the aid of fungal antibiotics.
The latter cause the immune system to produce the activer antibody, even to viruses! So fungal antibiotics help cure human viral infections – it is all due to the feedback system of the immune system: Which is positive, and very powerful.
With full AIDs, there is loads of the active antiviral in the blood, but it is dropped by the T cells, and never loaded on the macrophages. That is what the externally applied IL-2 will do: And cure AIDs, and remove all HIV infected cells from the body.
If some body is HIV-, we can spike the immune system: We take blood samples, and get at the active antiviral.
We give this in pill form, with no IL-10! The body will make IL-2 and IL-4, and we cure the infection totally!
And all this stuff is in the books! What medics needed was some stuff on systems work – which is my M.Eng.!
I am sorry I did no come to Cambridge: I was cleaver enough, and my sister and father in law got first in medicine from Kings. But I had no interest.
My head injury changed all that! A drip of IL-4+ will fix head injuries, and I am so interested in.
Polly has my cancer work, which will stand on its own. No way should I be in Salford singing on stage, and editing three internet blogs! What a waste.
An old idea was that HIV made IL-4 on its own – with no IL-2 or IL-1+. I was wrong! After I met the Cambridge students I learned that HIV made three chemokines, that normally are produced in response to IL-4.
The difference is the feedback – my area of expertise. IL-4 causes the APCs to produce the active antibody, and enough IL-2 to action it.
Chemokines make the antibody with no IL-2, only the usually suppressive IL-10. This is what causes AIDs!
So if somebody is HIV+, we give them a drip of IL-2, at the level of a person getting better from an infection, even with the aid of fungal antibiotics.
The latter cause the immune system to produce the activer antibody, even to viruses! So fungal antibiotics help cure human viral infections – it is all due to the feedback system of the immune system: Which is positive, and very powerful.
With full AIDs, there is loads of the active antiviral in the blood, but it is dropped by the T cells, and never loaded on the macrophages. That is what the externally applied IL-2 will do: And cure AIDs, and remove all HIV infected cells from the body.
If some body is HIV-, we can spike the immune system: We take blood samples, and get at the active antiviral.
We give this in pill form, with no IL-10! The body will make IL-2 and IL-4, and we cure the infection totally!
And all this stuff is in the books! What medics needed was some stuff on systems work – which is my M.Eng.!
I am sorry I did no come to Cambridge: I was cleaver enough, and my sister and father in law got first in medicine from Kings. But I had no interest.
My head injury changed all that! A drip of IL-4+ will fix head injuries, and I am so interested in.
Polly has my cancer work, which will stand on its own. No way should I be in Salford singing on stage, and editing three internet blogs! What a waste.
1 comment:
good blog sir
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